Unless Arsenal's French manager wants his final farewell to the Gunners after 22 years on the bench to be up in Huddersfield for the last game of the Premier League season, the English outfit are going to have to plough through a Ninja Warrior series of obstacles on Thursday.
Atletico Madrid have been handed a major injury boost ahead of their UEFA Europa League semi-final with Arsenal as the Rojiblancos have confirmed left-back Felipe Luis is fit again and available for selection.
Arsenal should feel an attacking side, and go into the game with an all-out attitude.
But there is no similar justification for Manchester United on Sunday, to play in second gear for most of that match except to assume that it was just a pattern that repeated itself like clockwork.
Arsenal's head of recruitment Sven Mislintat believes Liverpool's assistant manager Zeljko Buvac is the man to replace Arsene Wenger as manager.
"While their defence were to blame for giving away a silly goal at the Emirates in the first leg, Arsenal can score".
Angel Correa was sent off in the weekend game but is free to start against Arsenal.
Although Atletico Madrid are now leading arch-rivals Real Madrid in the La Liga table, the Rojiblancos are coming on the back of a rough string of fixtures. There was still the same buzz, he said, that had accompanied the first games of his long Arsenal tenure. "Ozil is the most risky player they have, because of his creativity and vision of the game".
"You always felt with the Arsenal players that they were all very comfortable".
Winning this title remains the only way for the north Londoners to stand a chance of playing in Europe next season as they now sit sixth on the log - 11 points behind fifth place Chelsea.
In that game, Arsenal looked on course to brilliant 1-0 home victory thanks to Alexandre Lacazette's second-half goal, only for a late lapse of concentration to allow Antoine Griezmann to score a late equaliser.
"We need positive energy and the stadium to explode", Simeone told a news conference.
The Gunners' head of recruitment is said to be keen to bring Liverpool's assistant manager to the Emirates Stadium as he believes the Bosnian will be flawless to complete the three-man team which includes himself, Buvac and Arsenal's head of football relations Raul Sanllehi. "You have seen my entire family back in Ghana and I am conscious to how we use to live so yeah some people forget where they come from but I have a mental picture of my father so I keep it as a reminder on my way to the top".