"We are aware of it", he said.
"All I can tell you is that we are no closer to sorting anything out", Wilshere said.
Arsenal won't be able to field exactly the same team that they did on Thursday-Sead Kolašinac has an ankle injury, although he hasn't officially been ruled out yet, and Nacho Monreal, whose place Kolašinac took in Milan, has a back issue.
Leipzig scored two second-half goals to seal the deal while the Russian outfit scored a crucial away goal through Domenico Criscito on Thursday evening, keeping the visitors' hopes alive for the second leg.
Watford beat Arsenal 2-1 at Vicarage Road in the reverse of the fixture previous year.
"Watford have won two of their last three games in all competitions at the Emirates and took all three points when the sides met at Vicarage Road earlier in the season thanks to an injury-time victor from Tom Cleverley".
The marvel in Milan may paper over a few cracks but it will not change the opinion of virtually every Arsenal fan that Wenger's time is up.
With this in mind, Watford defender Daryl Janmaat says it is important to widen the cracks in the Arsenal insecurities to earn a positive result against Wenger's men.
"You understand very well that if I responded to every single statement in the country I would already be mad - I am mad anyway, maybe, but I would be even more mad".
Atletico have reached two Champions League finals since winning the Europa League in 2012.
Arsenal lost to Swedish club Ostersunds in the Europa League last month but still advanced.
"I'm just unhappy that we lose the games; I want to win".
"However, managers and players don't always get to write their own happy ending and it would be disappointing to see someone with such an incredible career go out on such a low".
"We can't just give up in the Premier League, we've got to keep fighting", he said.
Welbeck put in a high-energy performance at the San Siro, although he still looked well short of confidence on the ball and lacked sharpness in his finishing. The offset from the United Kingdom will feel the same, but your clocks will say something different than what you're used to.
"There are some good teams left in it but we're confident in ourselves", said Wilshere.