Women's seventh seed Svetlana Kuznetsova found herself eliminated after a straight-sets loss to Garbine Muguruza, the 14th seed and 2015 victor at Wimbledon.
But now the 31-year-old is through to his second successive Wimbledon semi-final, where he will go up against seven-times champion Federer.
He had not beaten the 12-times grand slam victor since 2013, and had won just twice in 27 matches. I think on the centre court it's three women's matches and two men's matches every day. Instead, he said, scheduling decisions simply reflected what the spectators want to see.
However, Djokovic has now revealed the problem with his right elbow is by no means a new injury.
Djokovic lost the first set 7-6 and was trailing in the second 2-0 when he retired.
Djokovic is 25-2 all-time against Berdych.
The former World No 1 has endured a miserable 2017, much like his longtime rival Andy Murray. Murray was hampered by a sore hip.
Nadal played two of his four rounds this past week on Centre Court, and two on Court No. 1.
"Boris knows me very well. It was an opportunity and I'm sad it's over".
Mannarino has never before reached the quarterfinals at any of the four Grand Slam tournaments.
"I'm still in a state of shock".
The 12-times major victor said there was no point in going on when his serve and forehand were so severely undermined.
"I've been feeling better on the court in the last couple of months".
"He's been around for many years, and established top 10 player, understands the occasion of playing big matches", said Djokovic of Berdych.
Djokovic was also troubled with his shoulder.
Raonic said after the match that Federer is moving well, but that's not the only thing he has going for him.
Nadal added in the Spanish part of his press conference: "I like playing more on Centre Court".
"I didn't feel great during my last match".
"The level of pain was not decreasing, it was only increasing as the days went by".
Avenging last season's semi-final loss, Federer outclassed the robotic Canadian 7-4 6-2 7-6 (7-4).